Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKAVQVRKAYDLVTAEVKKPVLSKDDEVLVKVKRVGICGSDMHIYHGTNPLATLP-RVIGHEVTGQVEAVGANVQSLKPGDHVVIEPISYCGSCYACRKGRPNVCAKLSVFGV-----HEDGGMREYIVLP--ERQLHAVSKDLPWEEAVMA-EPYTIGAQAVWRGQVEKGDTVLIQGAGPIGICVLKMAKLAGAA-VMMTDLNNERLAFAKENGADAVVNVQAEHVAERVLEWTGNEGANVVIDAVCLPETFALSIEAVSPAGHVVVLGFDERAAQISQLPITK---KEVTITGSRLQTNQF-PKVVELLNGGRLMHNGLVTHTFSVDDVHHAFQFIKEHPDQVRKAVITFD 4CPD Chain:B ((1-333)) MRAVVFENKERVAVKEVNAPRLQHPLDALVRVHLAGICGSDLHLYHGKIPV--LPGSVLGHEFVGQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVYGYGPMFGNLQGAQAEILRVPFSNVNLRKLPPNLSPERAIFAGDILSTAYGGLIQGQLRPGDSVAVIGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGAIP-INAEQENPVRRVRSETNDEGPDLVLEAVGGAATLSLALEMVRPGGRVSAVGVDN--APSFPFPLASGLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYELF---------------

General information: TITO was launched using: RESULT: Template: 4CPD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1896 -225296 -118.83 -706.26 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain B : 0.78 3D Compatibility (PKB) : -118.83 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.473

(partial model without unconserved sides chains): PDB file : Tito_4CPD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CPD-query.scw PDB file : Tito_Scwrl_4CPD.pdb: