Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEHICGTSRIAGFRFSLYPMTDDFISVIKSALKKTDTSKVWTKTDHISTVLRGSIDHVFDAAKAIYLHAANSEQHIVMNGTFSIGCPGDTQGDTYLSKGDKRVNEDAVRGLKAEAPCQFALYPMNEPDYMGLIMEAVDIAKAQGTFVQGVHYASELDGDAHDVFSTLEAVFRMAEQQTNHITMTVNLSANSPSRKNRKQG 4H5B Chain:A ((2-153)) ---------------ETALLT---LDTLAKYLQEKEVQLDIEEN--------------------------GGQRFIRMGWRFEMGDAAVLVSVNDGPNNTSRLEITCVTQKTYADRRAEVAMMLNDRNRERAFARSID--QEGNVWLEYVGFYPTLAEMPQETFDTLFGGVLMHFQD--DYAALEGYVPQEGMQIQQPQA

General information: TITO was launched using: RESULT: Template: 4H5B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 648 -43349 -66.90 -285.19 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -66.90 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.073

(partial model without unconserved sides chains): PDB file : Tito_4H5B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4H5B-query.scw PDB file : Tito_Scwrl_4H5B.pdb: