Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRRFLLNVILVLAIVLFLRYVHYSLEPEPSNQPDTYSNFSSLAENESPADYDISYNEKKGSKVLIM------------------SPHGGRIEGGVSELVRYFNNEYSTYLF------EGLKSHDNQTLHITSTNFDEPLAKKKIKE-HQYVVAFHG-YKGENK-----------NTLVG-----GTDRKRAKMIVRALERRGFSAELASSKSGLAGLNAENINNQGETGLSIQLEISREQREAFFDDFYY-KNRKYTKNSEFYAYVSAIKGVLEKEYS------ 2Q7S Chain:A ((11-290)) IAPFTLALPEGEALPLVCDSPHSG-TFYPADFGAVVAPERLRGGEDTHVDALWEAVPRVGGTLLAATFPRVYIDPNRMLDDIDPAQLEGPWPTPLAPGTGLIWSNVDAPIYDRKLTVAEVQRRINRYYRPYHAALTEAVEGAYQRFGAVWHLNLHSMPNNAYERLKIQSPRPLADFVLGDRDGTTCEPGLVDLVERELREKGYTVARNDP---YKGQLIAQIGRPAERRNSLQIEIRRPL---------YMEEGTRERNEGFATLQRDLTLLTLRIAEYVRRGV

General information: TITO was launched using: RESULT: Template: 2Q7S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 978 -65873 -67.35 -296.73 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -67.35 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.297

(partial model without unconserved sides chains): PDB file : Tito_2Q7S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Q7S-query.scw PDB file : Tito_Scwrl_2Q7S.pdb: