Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTGYFLLEDGNKIEFELYPEAAPGTVANFEKLAN--EGF-YDGLTFHRVIPGFVSQGG-CPHGTGTGGPG-YTIKCETEGNPHTHEAGALSMAHAGKDTGGSQFFIVHEPQPHLNGVHTVFGKVTSGLEFAKNMSNGDVMKEVRVEG 1XQ7 Chain:B ((21-145)) ------------RVVIGLFGNDVPKTVENFKQLASGENGFGYKGSIFHRVIRNFMIQGGDFTNFDGTGGKSIYGTRFDDENLKIKHFVGAVSMANAGPNSNGSQFFVTTAPTPWLDGRHVVFGKVVEGMDVVKKVEN-----------

General information: TITO was launched using: RESULT: Template: 1XQ7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 574 15660 27.28 130.50 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain B : 0.76 3D Compatibility (PKB) : 27.28 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.459

(partial model without unconserved sides chains): PDB file : Tito_1XQ7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XQ7-query.scw PDB file : Tito_Scwrl_1XQ7.pdb: