Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAEITFKGGPVTLVGQEVKVGDQAPDFTVLTNSLEEKSLADMKGKVTIISVIPSIDTGVCDAQTRRFNEEAAKLGDVNVYTISADLPFAQARWCGANGIDKVETLSDHRDMSFGEAFGVYIKE--LR-LLARSVFVLDENGKVVYAEYVSEATNHPNYEKPIEAAKALVK 3HVS Chain:B ((4-167)) ---VHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFAGKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNNVITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYEAALAVLKA---

General information: TITO was launched using: RESULT: Template: 3HVS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 842 -63403 -75.30 -393.80 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : -75.30 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.580

(partial model without unconserved sides chains): PDB file : Tito_3HVS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HVS-query.scw PDB file : Tito_Scwrl_3HVS.pdb: