Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------------------------------------MRKKELFDFTNITPK----LFTELRVADKTVLQSFNFDEKNHQ--IYTTQVASGLGKDNTQSYRITRLSLEGLQLDSMLLKHGGHGTNIGIEN---------RNGTIYIWSLYDKPNETDKSELVCFPYKAGATLDENSKELQRF-----SNMPFDHRVTPALDMKNRQLAIR---QYDTKNNNNKQWVTIFN--------LDDAIANKNNPLYTIN-----IPDELHYLQGFFLDDGY-LYWYTGDTNSKSYPNLITVF---DSDNKIVLQKEITVGKDLSTRYENNFREPEGICMYTNPETGAKSLMV-------GITSGKEGNRISRIYAYHSYENFMNHVPMLRSPLLKTVGHQDTPPERFQPF-------------------IQTFILEYNAQNKKWMVPTSGYLPSYTSNLVR----------NITINADGNLQVTLNERYISLLHQ-------------SIEGDFRLKQKDIRMGSWYFAGGEKSNVLEIGFMKGSTK---------IRPDDAAISNASRMSIFMIVADKIEV--- 3OGZ Chain:A ((3-610)) NPSNSNLQALREELCTPGLDQGHLFEGWPETVDECNERQIALLTDLYMFSNMYPGGVAQYIRNGHELLARESEEVDFAALEMPPLIFEAPSLHRRTAERTALENAGTAMLCKTVFVLVAGGLGERLGYSSIKVSLPVETATNTTYLAYYLRWAQRVGGKEVPFVIMTSDDTHDRTLQLLRELQLEVPNLHVLKQGQVFCFADSAAHLALDETGKLLRKPHGHGDVHSLIYNATVAQPLVNDWLAAGYESIVFIQDTNAGATITIPISLALSAEHSLDMNFTCIPRVPKEPIGLLCRTKKNSGDPWLVANVEYNVFAEVSRALGFSPFPGSVNTLVFKLSSYVDRLRESHGIVPEFINPKYSDETRRSFKKPARIESLMQDIALLFSEDDYRVGGTVFERFSYQPVKNSLEEAAGLVAQGNGAYCAATGEAAFYELQRRRLKAIGLPLFYSSQPEVTVAKDAFGVRLFPIIVLDTVCASSGSLDDLARVFPTPEKVHIDQHSTLIVEGRVIIE--SLELYGALTIRGPTDSMALPHVVRNAVVRNAGWSVHAILSLCSRLSEVDRIRGFVLKKTAMAVMDC

General information: TITO was launched using: RESULT: Template: 3OGZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2303 28659 12.44 65.13 target 2D structure prediction score : 0.42 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 12.44 2D Compatibility (Sec. Struct. Predict.) : 0.42 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.200

(partial model without unconserved sides chains): PDB file : Tito_3OGZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OGZ-query.scw PDB file : Tito_Scwrl_3OGZ.pdb: