Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKRIILL------LAVIIAAAAAGVAFYVAK-DKGHEKAAD----VSV-NTESGDELLVSITDTDL---LTKYYENDKVIHEEKLTSYPAFALDQKQQVLY-YTGNNE-QNEMRLFKLDLKSHK----KTMLYKGAESADSLFLSKDRSTIYFRLGKADESNFRIAAF-DLKTKKYKNLYPAANDQDDTVSSFFYNQKNDSFAL-LHYSVEE-DYKKTDEANEKGIDPEPTTIHFAEGRQNKFNELKSLNQFISDIA-VSDDDKRILFTSYTQKGTEQTASIQMLNADTKKYE-SII-SNQKSFKLLIDAQPQFSKDGKNI-YFLAEAKGA-KKLKDETGREAKVRTIYSYSLENKTFKKVWENPNGIINSFFVIN---------------------- 4DIM Chain:A ((3-400)) DNKRLLILGAGRGQLGLYKAAKELGIHTIAGTMPNAHKPCLNLADEISYMDISNPDEVEQKVKDLNLDGAATCCLDTGIVSLARICDKENLVGLN--EEAAIMCGDKYKMKEAFKKYNVNTARHFVVRNENELKNALENLKLPVIVKATDLIYIA-KKEEEAIDGFNETMNLTKRDYCIVEEFIEGYEFGAQAFVYK--NDVLFVMPHGDETYMSHTAVPVGHYVPLDVKDDIIEKTKTEVKKAIKALGLNNCAVNVDMILKDNEVYIIELTGRVGANCLPELVEINYGIEYYKMIASMAISENPLVFWSQKSKENKAGLARMIIETEKSGILKEILNSNAKDDDIVEITFFKEENDEIKK-FENSNDCIGQIIVKEETLDKCKDKLDVIINNINIILK

General information: TITO was launched using: RESULT: Template: 4DIM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1692 -98180 -58.03 -287.07 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -58.03 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.235

(partial model without unconserved sides chains): PDB file : Tito_4DIM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DIM-query.scw PDB file : Tito_Scwrl_4DIM.pdb: