Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIGIIGGGSVGLLCAYYLS-LYHDVTVVTRRQEQAAAIQSEGIRLYKGGEEF-RADCS-ADTSINSDFDLLVVTVKQHQLQSVFSSLERI--GKTNILFLQNGMGHI-------------------HDLKDWHVGHSIYVGIVEHGAVRKSDTAVDHTGLGAIKWSAFDDAEPDRLNILFQH-NHSDFPIYYETDWYRLLTGKLIVNACINPLTALLQVKNGELLTTPAYLAFMKLVFQEACRILKLENEEKAWE-RVQAV-CGQTKENRSSMLVDVIGGR-QTEADAIIGYLLKEASLQGLDAVHLEFLYGSIKALERNTNKVF 3GHY Chain:A ((2-323)) TRICIVGAGAVGGYLGARLALAGEAINVLARG-ATLQALQTAGLRLTEDGATHTLPVRATHDAAALGEQDVVIVAVKAPALESVAAGIAPLIGPGTCVVVAMNGVPWWFFDRPGPLQGQRLQAVDPHGRIAQAIPTRHVLGCVVHLTCATVSPGHIRHGNGRRLILGEPAGGASPRLASIAALFGRAGLQAECSEAIQRDIWFKLWGNMTMNPVSVLTGATCDRILDDPLVSAFCLAVMAEAKAIGARIGCPIEQSGEARSAVTRQLGAFKTSMLQ-----RGPLEIDALVASVREIGLHVGVPTPQIDTLLGLVRLHAQTRG---

General information: TITO was launched using: RESULT: Template: 3GHY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1497 -226058 -151.01 -782.21 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -151.01 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.525

(partial model without unconserved sides chains): PDB file : Tito_3GHY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3GHY-query.scw PDB file : Tito_Scwrl_3GHY.pdb: