Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAGQPGHMPHGGSSNNLCHTLGPVHPPDPQRHPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRL--IPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHE-NGYNFKSDIWSLGCLLYEMAALQSPFYGDKM--NLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCICPDPHQRPDIGYVHQVAKQMHIWMSST 2WIH Chain:C ((5-234)) ----------------------------------------DMENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRL-DTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEF-----LHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDP

General information: TITO was launched using: RESULT: Template: 2WIH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -95330 for 1663 contacts (-57.3/contact) + 2D Compatibility (PS) -23622 + (NN) -7427 + (LL) 144 1D Compatibility (HY) -19200 + (ID) 4300 Total energy: -149735.0 ( -90.04 by residue) QMean score : 0.455

(partial model without unconserved sides chains): PDB file : Tito_2WIH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WIH-query.scw PDB file : Tito_Scwrl_2WIH.pdb: