Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQK-EVTFPANHTISQECKNLILQMLR-QATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 4CZU Chain:B ((13-270)) ------------------------YELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIAQIKREISTMKLIKHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDANGALKVSDFGLSAL----------PQQVREDGLLHDT---CGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPP--WFSASAKKLIKRILDPNPATRITFAEVIENEWFKKGYKAPKFEDDVDAIFDDSG--------------

General information: TITO was launched using: RESULT: Template: 4CZU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -170098 for 2009 contacts (-84.7/contact) + 2D Compatibility (PS) -26812 + (NN) -4827 + (LL) 2568 1D Compatibility (HY) -19600 + (ID) 4500 Total energy: -223269.0 ( -111.13 by residue) QMean score : 0.413

(partial model without unconserved sides chains): PDB file : Tito_4CZU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CZU-query.scw PDB file : Tito_Scwrl_4CZU.pdb: