Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKATAIAHTNVALIKYWGKRDEHLILPANSSLSFTVDKFYTKTTVEWDEKLTQDTFILNNEQ---KTDAKVARFIDKMREEFGISAKAKITSENHVPTAAGLASSASAFAALALAGSNAAGRKDTKEYISRLARFGSGSASRSVFGDFVIWEKGELADGSDSFAVPFTNKLCDK-MSLVVAVVSDKEKKVSSRDGMRLTVETSPFFENWVSAAEIDLEEMKQAILDEDFIKVGEITERNGMKMHATTLGAEPPFTYFQPQSLEIMDAVRELRENGIPAYFTMDAGPNVKVICERANENIVAEKLSGLAKNVLICHAGKEASVVSDEK 4DU8 Chain:B ((12-309)) ----ARAHTNIALIKYWGKADETYIIPMNNSLSVTLDRFYTETKVTFDPDFTEDCLILNGNEVNAKEKEKIQNYMNIVRDLAGNRLHARIESENYVPTAAGLASSASAYAALAAACNEALSLNLSDTDLSRLARRGSGSASRSIFGGFAEWEKGH--DDLTSYAHGINSNGWEKDLSMIFVVINN------SRSGMSLTRDTSRFYQYWLDHVDEDLNEAKEAVKNQDFQRLGEVIEANGLRMHATNLGAQPPFTYLVQESYDAMAIVEQCRKANLPCYFTMAAGPNVKVLVEKKNKQAVMEQF-----------------------

General information: TITO was launched using: RESULT: Template: 4DU8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -78199 for 2443 contacts (-32.0/contact) + 2D Compatibility (PS) -31884 + (NN) -11661 + (LL) 2728 1D Compatibility (HY) -22800 + (ID) 7100 Total energy: -148916.0 ( -60.96 by residue) QMean score : 0.476

(partial model without unconserved sides chains): PDB file : Tito_4DU8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DU8-query.scw PDB file : Tito_Scwrl_4DU8.pdb: