Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLSKQLYKS--LPLLTVVLCVGALQQNVEAKAKHYKTTSHVETQYVS------------------------------TSSKKILPF----------THNKQIKVGPLDNLGRATYSHIQLRDADEPKIKRE-RLTY--------------NPTGWHNYKFTTEKGKTTW-------LMDRGHLVGYQFSGMNN---------VPENLVTMTKYLNTGFS-------------ENNPDGMLYYENRLDSWLANHKNFWLDYKVTPIYEGN---NLVPSRVEL---QYVGIDKQGKL--LEIKLGGGKEQTDEYGVTTVTLENTSP---LAKIDYKTGMLIKEDGKQAEEGEDPNSDADENEAAIESAS--DIEENTNTNTSESDTNNVAPKNRIVYVANKGRSNTYWYSLENIKNANTANIVQMTEQEALNQHKHHSTTEAQ 3J0C Chain:A ((1-442)) YEHATTMPSQAGISYNTIVNRAGYAPLPISITPTKIKLIPTVNLEYVTCHYKTGMDSPAIKCCGSQECTPTYRPDEQCKVFTGVYPFMWGGAYCFCDTENTQVSKAYVMKSDDCLADHAEAYKAHTASVQAFLNITVGEHSIVTTVYVNGETPVNFNGVKITAGPLSTAWTPFDRKIVQYAGEIYNYDFPEYGAGQPGAFGDIQSRTVSSSDLYANTNLVLQRPKAGAIHVPYTQAPSGFEQWKKDKAPSLKFTAPFGCEIYTNPIRAENCAVGSIPLAFDIPDALFTRVSETPTLSAAECTLNECVYSSDFGGIATVKYSASKSGKCAVHVPSGTATLKEAAVELTEQGSATIHFSTANIHPEFRLQICTSYVTCKGDCHPPKDHIVTHPQYHAQTFTAAVSKTAWTWLTSLLGGSAVIIIIGLVLATIVAMYVLTNQKHN

General information: TITO was launched using: RESULT: Template: 3J0C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 53826 for 2107 contacts (25.5/contact) + 2D Compatibility (PS) -34739 + (NN) 13949 + (LL) 0 1D Compatibility (HY) -7200 + (ID) 2600 Total energy: 23236.0 ( 11.03 by residue) QMean score : 0.135

(partial model without unconserved sides chains): PDB file : Tito_3J0C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3J0C-query.scw PDB file : Tito_Scwrl_3J0C.pdb: