Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITLKSAREIEAMDRAGDFLASIHIGLRDIIKPGVDMWEVEEYVRRR-CKEENVLPLQIGVDGAVMDYPYATCCGLNDEVAHAFPRHYTLKQGDLLKVDMVLSEPLDKSIVDVSSLNFDNVAQMKKYTETYSGGLADSCWAYAVGEVSQEVKDLMSVTREAMYIGIEKAVIGNRIGDIGAAIQDYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLREGMVLTIEPMINTGTWEIDTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTSQGEERTY 4FO8 Chain:D ((3-253)) -VTIKTPDDIEKMRIAGRLAAEVLEMIGEHIKPGVTTEELDRICHDYIVNEQKAIPAPLNYKG----FPKSICTSINHVVCHGIPNEKPLKEGDILNVDITVIK------------------------DGYHG---DTSKMFLVGKTPEWADRLCQITQECMYKGISVVRPGAHLGDIGEIIQKHAEKNGFSVVREYCGHGIGKVFHEEPQVLHYGRAGTGIELKEGMIFTIEPMINQGRPETRL-LGDGWTAITKDRKLSAQWEHTVLVTADGYEILTLRNDETFP

General information: TITO was launched using: RESULT: Template: 4FO8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -136207 for 2175 contacts (-62.6/contact) + 2D Compatibility (PS) -26741 + (NN) -9689 + (LL) 2208 1D Compatibility (HY) -16000 + (ID) 4900 Total energy: -191329.0 ( -87.97 by residue) QMean score : 0.491

(partial model without unconserved sides chains): PDB file : Tito_4FO8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FO8-query.scw PDB file : Tito_Scwrl_4FO8.pdb: