Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNRDQEKIQ---IENEMNAMHGT-------IKEDILKDFEEFKGYLKKQV--NRGKKLGL---------------------DDGKLVKS----------------AAILG-D-----YLAKHEEPQNG-EEMLLQELWSVA-DEDEKEHLAQLLVKLVD-K-Q 4QT6 Chain:A ((1-157)) -GFDPEKAQCCLVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPCVMFYSSNPGE---KVKICDMQMR

General information: TITO was launched using: RESULT: Template: 4QT6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 381 -17514 -45.97 -176.91 target 2D structure prediction score : 0.24 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -45.97 2D Compatibility (Sec. Struct. Predict.) : 0.24 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.060

(partial model without unconserved sides chains): PDB file : Tito_4QT6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QT6-query.scw PDB file : Tito_Scwrl_4QT6.pdb: