Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKAVIAKNEEQLKDAFYVREEVFVKEQN-VPAEEE-I-DE-LENESEHIVVYDGEKPVGAGRWRMK----------------DGYGKLERICVLKSHRSAGVGGIIMKALEKAAADG-GASGFILNAQTQAVPFYKKHGYRVLSEKE-FLDAGIPHLQMMKD 1KUX Chain:A ((37-192)) ---FRCLTPEDAAGVFEIEREAFISVSGNCPLNLDEVQHFLTLCPELSLGWFVEGRLVAFIIGSLWDEERLTQESLALHRPRGHSAHLHALAVHRSFRQQGKGSVLLWRYLHHVGAQPAVRRAVLMCEDALVPFYQRFGFHPA-GPCAIVVGSLTFTEMH--

General information: TITO was launched using: RESULT: Template: 1KUX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 580 -92779 -159.96 -692.38 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -159.96 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.373

(partial model without unconserved sides chains): PDB file : Tito_1KUX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KUX-query.scw PDB file : Tito_Scwrl_1KUX.pdb: