Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTGYFLLEDGNKIEFELYPEAAPGTVANFEKLAN--EGF--------YDGLTFHRVIPGFVSQGG-CPHGTGTGGPG-YTIKCETEGNPHTH-EAGALSMAHAGKDTGGSQFFIVHEPQPHLNGVHTVFGKVTSGLEFAKNMSNGDVMKEVRVEG 4HY7 Chain:A ((19-149)) ------------RIVMELYKDAVPRTVENFRALCTGEKGVGKSGKPLHYKGSAFHRVIPDFMCQGGDFTRGNGTGGESIYGEKFADEKFVHKHTKPGILSMANAGPNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNI-------------

General information: TITO was launched using: RESULT: Template: 4HY7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 563 -3208 -5.70 -27.19 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -5.70 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.502

(partial model without unconserved sides chains): PDB file : Tito_4HY7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HY7-query.scw PDB file : Tito_Scwrl_4HY7.pdb: