Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMTGTLGTLVPIILMFAVLYFLLIRPQQKQQKAVRQMQEELKKGDSVVTIGG----LHGTVDSIDESKVVIKTG-DN--TRLTFDRRAIREVSAAE 2E6Z Chain:A ((418-467)) --------------------------------------SGFQPGDNVEVCEGELINLQGKILSVDGNKITIMPKHEDLKDMLEFPAQE--------

General information: TITO was launched using: RESULT: Template: 2E6Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 104 20181 194.05 469.33 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.56 3D Compatibility (PKB) : 194.05 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.56 QMean score : 0.648

(partial model without unconserved sides chains): PDB file : Tito_2E6Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2E6Z-query.scw PDB file : Tito_Scwrl_2E6Z.pdb: