Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTHVRFDYSKALTFFNEHELTYLRDFVKTAHHNIHEKTGAGSDFLGWVDLPEHYDKEEFARIKKSAEKIKS---------DSDVLLVVGIGGSYLGARAAIEALNHAFYNTLPKAKRGNPQVIFIGNNISSSYMRDVMDLLEDVDFSINVISKSGTTTEPAIAFRIFRKLLEEKYGKEE--AKARIYATTDKERGALKTLSNEEGFESFVIPDDVGGRYSVLTAVGLLPIAV-SGVNI-DDMMKGALDASKDFATSELEDNPAYQYAVVRNVLYN-KGKTIEMLINYEPALQYFAEWWKQLFGESEGKDE----------KGIYPSSANYSTDLHSLGQYVQEGRRDLFETVLNVEKPKHELTIEEA-DNDLDGL---------NYLAGKTVDFVNKKAFQGTMLAHT--DGNVPNLIVNIPELNAYTFGYLVYFFEKACAMSGYLLGVNPFDQPGVEAYKVNMFALLGKPGFEEKKAELEKRLED 3UJH Chain:A ((127-536)) ---------------------------------------------------------VLRRIRVFSEKVRSGEIRGHTGKKLVNVISIGIGGSYLGTEFVHLALAAEGYAAE---KAHGRQIHFL-ANVDPVDVWLAERGFDPEETLVVVISKTFTTAETMMNARSVRDWYLHHYKGDERALGAHFCAVSTNLDGTS-KFG-IQSDRVFGFWDWVGGRYSVTSAVGILPLALQYGYDVAQEFLNGAHAMDVHFKTAELADNLPMLMGLISVWNATFFGYSNVAVLPYAQALLRFPAHIQQLTMESNGKRVTMDGKTLDFDVGEIFFGEPGTNGQHSFYQLIHQGR-VIPAEFIGFCKSQRAIKLKEEPVSNHDELMSNFFAQPDALAFGKTPEELRKEGIPEKLVPHKTFPGDRPSCMLLFPEISPFHIGQLLALYEHRVAVEGWLWGINSFDQWGVELGKVLAKGVRGILQKR------------

General information: TITO was launched using: RESULT: Template: 3UJH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1883 16214 8.61 43.35 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 8.61 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.430

(partial model without unconserved sides chains): PDB file : Tito_3UJH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UJH-query.scw PDB file : Tito_Scwrl_3UJH.pdb: