Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQQLKDIISACDLAIQNEDFDTLMNYYSEDAVLVVKPGMIARGKEEIKKAFITIANYFNHHIVPTQGKMILL-EAGDTVLVLSQTLLDSD-KKDSEYAMERRATYVFKKNAQGEWLCVIDNSYGTDLIGV 3CU3 Chain:A ((15-138)) -ESAIRAFHRQMIDAWNRGSGEGFAAPFSETADFITFEGTHLKGRKEIAAFHQQAFDTVVKGTRLEGEVDFVRFVNSQLALMLVVIRVILPGQTETSASRDSLPLYVVTKG-DEGWQIEGLLNTRK-----

General information: TITO was launched using: RESULT: Template: 3CU3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 525 -37230 -70.91 -305.16 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -70.91 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.390

(partial model without unconserved sides chains): PDB file : Tito_3CU3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CU3-query.scw PDB file : Tito_Scwrl_3CU3.pdb: