Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLRTEKEKMAAGELYNSEDQQLLLERKHARQLIRQYNET-PEDDAVRTKLLKELLGSVGDQVTILPTFRCDYGYHIHIGDHTFVNFDCVILDVCEVRIGCHCLIAPGVHIYTAGHPLDPIERKSGKEFGKPVTIGDQVWIGGRAVINPGVTIGDNAVIASGSVVTKDVPANTVVGGNPARILKQL 1KQA Chain:C ((7-185)) ------ERIRAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEVEKRESLIKEMFATVGENAWVEPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGAGSIVTKDIPPNVVAAGVPCRVIREI

General information: TITO was launched using: RESULT: Template: 1KQA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 898 -58220 -64.83 -327.08 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain C : 0.82 3D Compatibility (PKB) : -64.83 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.676

(partial model without unconserved sides chains): PDB file : Tito_1KQA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KQA-query.scw PDB file : Tito_Scwrl_1KQA.pdb: