Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVKAGNETQISEFLLLGFSEKQELQPFLFGLFLSM-YLVTVLGNLLIILAAISDSCLHTPMYFFLSNLSFVDICFASTMVPKMLVNIQTQSKVITYAGCITQMCFFVLFIVLDSLLLTVMAYDQFVAICHPLHYTVIMSPQLCGLLVLVSWIMSVLNSMLQSLVTLQLSFCTDLEIPHFFCELNEMIHLACSDTFVNNMVMHFAAVLLDGGPLVGILYSYCRIVSSIRAISSTQGKYKALSTCASHLSVVSIFYGTGLGVYLSSTMTQNLHSTAVASVMYTVVTPMLNPFIYSLRNKDIKGALTQFFRGKQ 4LDE Chain:A ((186-376)) -----------------------------GIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILTKTWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFL----PIQMHWYRATHQEAINCYAEE----TCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKFALKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLC

General information: TITO was launched using: RESULT: Template: 4LDE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -161324 for 1321 contacts (-122.1/contact) + 2D Compatibility (PS) -19197 + (NN) -3603 + (LL) 3584 1D Compatibility (HY) -14400 + (ID) 2400 Total energy: -197340.0 ( -149.39 by residue) QMean score : 0.192

(partial model without unconserved sides chains): PDB file : Tito_4LDE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LDE-query.scw PDB file : Tito_Scwrl_4LDE.pdb: