Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMDFYIKQIIIHQFSPNDTELVLSDTPLTLTPRIDDYFRKKLSKVFSDEAKRGYFGEDNVFMSHLQDDLYVSSCQIAQLWKEEFVISEDQKTNDLVFIQFDKDGMEHFAFLRI--SLKEQFAHVSENQEQPITITQNNLPSAAQTPDEALVVNKSSKQYYLIEKRIKHNGSFANYFSENLLQVQPEQSVKKS-IKMVEQTAQKIAENFNKDDFSFQSKMKSAIYKNLEEEQELSPEKLADQLFDDNLTARLTFVDELKDAIPGPVQVSDIDHSRQIKKLENQKLSLSNGIELIVPNNVYQDAESVEFIQNPDGTYSILIKNIQDIQNK 2IPC Chain:A ((694-800)) ------------------------------------------------------------------------------------------------YVSFDDDLMRLFASDRVIAMLDRMGFDDSEPIEHPM-VTRSIERAQKRVEDRNFAIRKQLLQFDDVLSRQRE----VIYAQRRLILLGKDEEVKEAAIGMVEETVASLAENFLNPEVHPEDWDLEGLKATLLDTAPQLQDFPFAELRALKAEEAVERLVEAALKAYEAREAELSPPLMRAVERFVILNVVDNAWKEHLHNLDVLRQGIFLRGYGQKDPFQEYKIEATRLFNE

General information: TITO was launched using: RESULT: Template: 2IPC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 14595 for 491 contacts (29.7/contact) + 2D Compatibility (PS) -10700 + (NN) 1457 + (LL) 6860 1D Compatibility (HY) -5200 + (ID) 1500 Total energy: 5512.0 ( 11.23 by residue) QMean score : 0.177

(partial model without unconserved sides chains): PDB file : Tito_2IPC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IPC-query.scw PDB file : Tito_Scwrl_2IPC.pdb: