Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKQVYIIHGYRASSTNHWFPWLKKRLLADGVQADILNMPNPLQPRLEDWLDTLSLYQH--------------TLHENTYLVAHSLGCPAILRFLEHLQLRKQLGGIILVSGFAKSLPTLQMLDEFTQGSFDHQKIIESAKHRAVIASKDDQIVPFSFSKDLAQQIDAALYEVQHG-GHFLEDEGFTSLPIVYDVLTSYFSKETR 3QMM Chain:A ((6-169)) ----VVMVHGIGGSSSN--FEGIKSYLVSQGWSRDKLYA-------VDFWDKTGTNYNNGPVLSRFVQKVLDETGAKKVDIVAHSMGGANTLYYIKYLDGGNKVANVVTLGG-ANRLTT----DKAPPGTDPNQKILYTS-----IYSSDDEIVPNYLSR-----LDGARNVQIHGVGHM----GLLYSPQVYSLI---------

General information: TITO was launched using: RESULT: Template: 3QMM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 855 -103612 -121.18 -695.38 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -121.18 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.272

(partial model without unconserved sides chains): PDB file : Tito_3QMM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QMM-query.scw PDB file : Tito_Scwrl_3QMM.pdb: