Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDIADQTFVKKVNQKLLLKEILKNSPISRAKLSEMTGLNKSTVSSQVNTLMKENLVFEIGQGQSSGGRRPVMLVFNKKAGYSIGIDVGVDYISGILTDLEGTIILDQHHHLESNSPEITKDI---LIDMIHHFITRMPQSPYGLIGIGICVPGLID-KNQKIVFTPNSNWRDID-LKSFIQEKFNVPVFIENEANAGAYGEKVFGAAKNHNNIIYASISTGIGIGVIINNHLYRGVSGFSGEMGHMTIDFNGPKCSCGNRGCWELYASEKAL----------------LKSLQTKEKKVSYQDIIDLAHLNDIGTLNALQNFGFYLGIGLTNILNTFNPQAIILRNSIIESHPMVLNSIRSEVSSRVYPQLGNSYELLPSSLGKNAPALGMSSIVIEHFLDIVKM 2QM1 Chain:A ((9-321)) ----------------------------------------------------------------------------------IGIDLGGTTIKFAILTTDG--VVQQKWSIETNILEDGKHIVPSIIESIRHRIDLYNMKKEDFVGIGMGTPGSVDIEKGTVVGAYNLNWTTVQPVKEQIESALGIPFALDNDANVAALGERWKGAGENNPDVIFITLGTGVGGGIVAAGKLLHGVAGCAGEVGHVTVDPNGFDCTCGKRGCLETVSSATGVVRVARHLSEEFAGDSELKQAIDDGQDVSSKDVFEFAEKGDHFALMVVDRVCFYLGLATGNLGNTLNPDSVVIGGGVSAAGEFLRSRVEKYFQEFTFPQVRNSTKIKLAELGNEAGVIGAASLALQ--------

General information: TITO was launched using: RESULT: Template: 2QM1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1647 -189479 -115.04 -648.90 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -115.04 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.510

(partial model without unconserved sides chains): PDB file : Tito_2QM1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QM1-query.scw PDB file : Tito_Scwrl_2QM1.pdb: