Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYK--------GQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG 2YCX Chain:A ((15-283)) -------SLLMALVVLLIVAGNVLV-IAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPGCCDF--VTNRAYAIASSIISFYIPLLIMIFV---ALRVYREAKEQIRKIDR----ASKRKRVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNW-LGYANSAMNPIIYCRSPDFRKAFK---------------------------------------------

General information: TITO was launched using: RESULT: Template: 2YCX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -220151 for 1932 contacts (-113.9/contact) + 2D Compatibility (PS) -26688 + (NN) -7308 + (LL) 5116 1D Compatibility (HY) -28400 + (ID) 3800 Total energy: -281231.0 ( -145.56 by residue) QMean score : 0.333

(partial model without unconserved sides chains): PDB file : Tito_2YCX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YCX-query.scw PDB file : Tito_Scwrl_2YCX.pdb: