Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCV---GGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE 2Y02 Chain:A ((23-300)) ------------------------------------------LLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVS---FLPIMMHWWRDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQ------------SRV------MLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGYANSAMNPIIYCR-SPDFRKAFKRLLA----------------

General information: TITO was launched using: RESULT: Template: 2Y02.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -247634 for 1945 contacts (-127.3/contact) + 2D Compatibility (PS) -26069 + (NN) 163 + (LL) 5020 1D Compatibility (HY) -24800 + (ID) 4600 Total energy: -297920.0 ( -153.17 by residue) QMean score : 0.343

(partial model without unconserved sides chains): PDB file : Tito_2Y02.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y02-query.scw PDB file : Tito_Scwrl_2Y02.pdb: