Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISTSEHSIFKNPAKNDGLRVRTIEVSEKFTSSAQNSDTIKKVVSQNNGHVLPIIAQFLLDNTNDVTSLFQKEDSVFYQLLSTESSNTGIRMIKHYATLTTTAHILNQSLDLQLNVSSIKNYLLSYHNETVSERS--LADKAMDTIVQFIAENLGKFSQQTRLANMIQNFGILSLKDDYIEVKIIRNVFDKMLTDSQFEDTKNVIDALDNAGKLVSDRDRKTTKRNAKDDTGKSTSLVFYQIKIDLDYADVLGLQSQGRDNVIQKHSNPSQFKNTNLEEFMKSENTTLIVF 4FDG Chain:B ((185-294)) ----------------------------------------------------------------------------------------------------------------QFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILED--DLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIYMKVSSIEVSQKVLDEV-----IISEEDEKKIKDLAKD--------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4FDG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 13712 for 502 contacts (27.3/contact) + 2D Compatibility (PS) -10813 + (NN) 3246 + (LL) 11140 1D Compatibility (HY) -6000 + (ID) 1400 Total energy: 9885.0 ( 19.69 by residue) QMean score : -0.054

(partial model without unconserved sides chains): PDB file : Tito_4FDG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FDG-query.scw PDB file : Tito_Scwrl_4FDG.pdb: