Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTHSFAVPRSVEWKETAITILNQQKLPDETEYLELTTKEDVFDAIVTLKVRGAPAIGITAAFGLALAAKDIETDNVTEFRRRLEDIKQYLNSSRPTAINLSWALERLSHSVENAISVNEAKTNLV----HEAIQIQVEDEETCRLIGQNALQLFKKGDRIMTICNAGSIATSRYGTALAPFYLAKQKDLGLHIYACETRPVLQGSRLTAWELMQGGIDVTLITDSMAAHTMKEKQISAVIVGADRIAKNGDTANKIGTYGLAILANAFDIPFFVAAPLSTFDTKVKCGADIPIEERDPEEVRQISGVRTAPSNVPVFNPAFDITPHDLISGIITEKGIMTGNYEEEIEQLFKGEKVH 1T9K Chain:A ((8-344)) --------KTMEWSGNSLKLLDQRKLPFIEEYVECKTHEEVAHAIKEMIVRGAPAIGVAAAFGYVLGLRDYKTGSLTDWMKQ---VKETLARTRPTAVNLFWALNR----MEKVFFENADRENLFEILENEALKMAYEDIEVNKAIGKNGAQLIKDGSTILTHCNAGALATVDYGTALGVIRAAVESGKRIRVFADETRPYLQGARLTAWELMKDGIEVYVITDNMAGWLMKRGLIDAVVVGADRIALNGDTANKIGTYSLAVLAKRNNIPFYVAAPVSTIDPTIRSGEEIPIEERRPEEVTHCGGNRIAPEGVKVLNPAFDVTENTLITAIITEKGVIRPPFEENIKKILE-----

General information: TITO was launched using: RESULT: Template: 1T9K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2039 -180619 -88.58 -542.40 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -88.58 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.509

(partial model without unconserved sides chains): PDB file : Tito_1T9K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1T9K-query.scw PDB file : Tito_Scwrl_1T9K.pdb: