Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRILFIGDVVGSPGRDMVKEYVPKLKTKYKPHFTIINGENAAHGKGLTEKIYHSLIQSGADAITMGNHTWDKKEIFDFIDDVPNLVRPANFPEGTPGKGITYVKANGKELAVINLQGRTFLPPLDDPFLKADELIAEAAKRTPYIFIDFHAEATSEKLALGWYTDGRASAVVGTHTHVQTADNRILPKGTAYITDVGMTGPYDGILGMDRETIIKRFKTNLPVRFTVAEGKTTLSGVVIDIDDQTKKAVKIERILINDDHMFFE 2CV9 Chain:A ((2-227)) -RVLFIGDVMAEPGLRAVGLHLPDIRDRYD--LVIANGENAARGKGLDRRSYRLLREAGVDLVSLGNHAWDHKEVYALLESEP-VVRPLNYPPGTPGKGFWRLEVGGESLLFVQVMGRIFMDPLDDPFRALDRLLEE--EKADYVLVEVHAEATSEKMALAHYLDGRASAVLGTHTHVPTLDATRLPKGTLYQTDVGMTGTYHSIIGGEVETFLARFLTGRPQPFRAAQGKA--------------------------------

General information: TITO was launched using: RESULT: Template: 2CV9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1277 -107041 -83.82 -473.63 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -83.82 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.576

(partial model without unconserved sides chains): PDB file : Tito_2CV9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CV9-query.scw PDB file : Tito_Scwrl_2CV9.pdb: