Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHRLLLLMMLTALGVAGCGQKKPPDPPNRVPEKKVVETSAFGHHVQLVNREGKAVGFIEIKESDDEGLDIHISANSLRPGASLGFHIYEKGSCVRPDFESAGGPFNPLNKEHGFNNPMGHHAGDLPNLEVGADGKVDVIMNAPDTSLKKGSKLNILDEDGSAFIIHEQADDYLTNPSGNSGARIVCGALLGNNEKQ 1XTM Chain:B ((18-170)) --------------------------------------SAFGHHVQLVNREGKAVGFIEIKESDDEGLDIHISANSLRPGASLGFHIHEKGSCVRPDFESAGGHFNPLNKEHGFNNPMGHHAGDLPNLEVGADGKVDVIMNAPDTSLKKGSKLNILDEDGSAFIIHEQADDYLTNPSGNSGARIVCGALLG-----

General information: TITO was launched using: RESULT: Template: 1XTM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 874 -71546 -81.86 -467.62 target 2D structure prediction score : 0.81 Monomeric hydrophicity matching model chain B : 0.89 3D Compatibility (PKB) : -81.86 2D Compatibility (Sec. Struct. Predict.) : 0.81 1D Compatibility (Hydrophobicity) : 0.89 QMean score : 0.582

(partial model without unconserved sides chains): PDB file : Tito_1XTM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XTM-query.scw PDB file : Tito_Scwrl_1XTM.pdb: