Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLNQKALNSYVYTLAFSSLSFGLI---FGLYLFV-----YSGFMA---------IALVTIAIIAFYALITYLVFAAPL--QVWLRRRRRKFSLIN-FLIYIAVAFSAVFLFWFVDYPPNALTMFRSFEYYIMSIVAAFIYWFWDSIFLRN 2Y02 Chain:A ((43-177)) ----QTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQD------------------------

General information: TITO was launched using: RESULT: Template: 2Y02.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 267 -51841 -194.16 -503.31 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -194.16 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.378

(partial model without unconserved sides chains): PDB file : Tito_2Y02.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y02-query.scw PDB file : Tito_Scwrl_2Y02.pdb: