Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLGIDMNVKESVLCIRLTGELDHHTAETLKQKVTQSLEKDDIRHIVLNLEDLSFMDSSGLGVILGRYKQIKQIGGEMVVCAISPAVKRLFDMSGLFKIIRFEQSEQQALLTLGVAS 1TH8 Chain:B ((2-116)) -SLAIDLEVKQDVLIVRLSGELDHHTAEELREQVTDVLENRAIRHIVLNLGQLTFMDSSGLGVILGRYKQIKNVGGQMVVCAVSPAVKRLFDMSGLFKIIRVEADEQFALQALGVA-

General information: TITO was launched using: RESULT: Template: 1TH8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 541 -108384 -200.34 -942.47 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain B : 0.94 3D Compatibility (PKB) : -200.34 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.94 QMean score : 0.628

(partial model without unconserved sides chains): PDB file : Tito_1TH8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1TH8-query.scw PDB file : Tito_Scwrl_1TH8.pdb: