TITO

Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)

Input alignment information:

Query sequence

MAKLTATFELHDKISRKLRMIQGNAERLKRAANGPLIFEAEDRTERVMRQIDRSANRLTARARLLEMGLDDRVSNGLHSIRQQAEDLTEGSHEVTVSVNDQATPRFRLIRGGLTDLNSSHAEPTVSVRDHASNQLDEIRRHVTDVDSEHAEPTVSIKDRASAALDAIEAKIDSLKGATITLAVAGGFSAGSIMGSGKSTMSQDAYVSATSNVNKKDVAKMTDQIYFNNKAGSSREEVSLSLRNLSQQTGASKKALAELTESSSKIAQLMNADQAEVDRAFSSMYNNLKLSGKQSGDLIAYVYRNAGDQADDLLDTMNEYSSTFKDLKLTGGQIANAMIKGTKGGARNFDNLADSMREFNIRRTEMSDSQVDAFKTLFGAKETKKMFKGFKDGSISGEESLFRVAKALSKVKDKTKRAAIATELIGTQYEDLKQPILDMAEGIGTSAKTSGELERSFTKLRDNNPMTPVNDAMRDFESISKDMGTSLLTGLGPAFDKISSFINSKEGQEKLKEIKKDIADLGEEIGDKLNVAIEWSVNHWDDLKTAIKVVIPSLIGLIGYLKILRPLLKGIGTVGSDAAGVIRKLIPKRTPKAGTNTQSERRNRNSNRNASTRGRESKTATGPTSLPRSGSLTYCCCSDGGKNDRIRRRRGKRVLGRRGNPNRMNPSDSSIAVSSERLERRRSGRTVGTNPTRDSRSAIITTRSELYSAGRAAGGTSKFGKVLSPLKSVGKFAKGVPLLGTALAATDLIGMNKDNVGEKIGSAGGGLAGAATGAAIGSVIPGVGTAIGGLVGGIAGTMGGSSLGKAFDGSEVKKKLNSTLFDQKWWSEKWSGIKSNAKTSINGLSDTWSNVKEKVKSTLFNSEWWSEKWSGVKSWAQNKWNSASSVWESVKGKIK-STLFSEKWWSGKWEGVKSWAQSKWDSASSVWQSVKGKLKSTLFSEKWWSG--KWESVKSWSKNKWDNA-KSIWKSVKSSISETLFSKKWWSEKWQSVKELGSSILGGVKEVGGKVASSAKKTAGKAWGYVKSGVNYLFGSGKEKPKKHATGGYITKPTISWIGEAGKEFVIPVENNKGRGKMLLSQAASKLGMSVVDDIASASSAGGEPATSPLVRSAAVTASVSPIIDTSSLDEQATSFGQQFTKSFDQGIRDNVVSMEAWKQKNVGQPMNNLISYSPNYGKQVVNGYAKGQNSTSTGTDGFLQTKVKMPFQNTVNKSSSWGSGTIKGFASGQNSSQTGTDQYVSTHINKPFIRSKESSNGWGSGMIGNFVSGMTSKASEVNEAAKELAKKVEKAFREELDIHSPSRVMMSLGRFASIGIVKGLDSVDVKKFAEKQAGSLAAAYSGMGAVSGNVKQWLMAAIMATKTPMSWLPGLMTIAQHESGGNPKAINLWDSNAKAGHPSQGLMQTIPSTFNAHKLPGMNNILNPIHNAAAAIGYIKSRYGSINNVPGIRSMRHGGPYVGYANGGLITKEQIARVGEGNKREWIIPEERGIRGRYLLAQAAKALGMEVTDPSEKGQTELSSGQVTAATTGRNQTTFKAAGGKEVIIQFNGDQHFHNDQDMNSLVAKIKQALVDELEQDINIGTKGVVAFD

4O94 Chain:A ((203-320))

----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVDGQENTWSNI-----------------------FSQKFYEVQKDITESDHGVIDYMVVVNAKWWNGLSKDLQDAMKKAMDEATKVNNDVAGKLNDEAKQKIASSGASKIHQLTPEQRKQWVEAMKPVWAKFESAIGKDL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information:

TITO was launched using:	RESULT:
Template: 4O94.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output	Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 206 11694 56.77 102.58 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain A : 0.55 3D Compatibility (PKB) : 56.77 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.55 QMean score : 0.315

(partial model without unconserved sides chains):
PDB file : Tito_4O94.pdb:

(Unconserved sides chains are recalculated) :
Sequence: align-4O94-query.scw
PDB file : Tito_Scwrl_4O94.pdb: