Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKITFIGAGSTIFAKNVLGDCLLTEALNGFEFALY--DIDPKRLQESQLMLENLRDRYNPSVAINSYDDRKLALQNAGYVINAI--------QVGGYKPSTVIDFEIPKRYGL-----RQTIADTVGIGGIFRSLRTIPVLFDIAKDMEEMCPDAWFLNYTNPMATLTGAMLRYTNIKTIGLCHSVQVCTKDLFKALGMEHDGIEERIAGINHMAWLLEVKKDGTDLYP-------------EIKRRAKEKQKTKHHDMVRFELMDKFGYYV---TESSEHNAEYHPYFIKRNYPELISELQIP-LDEYPRRCVKQIENWEKMRDDIVNNKNL----THER-------SKEYGSRIIEAMETNEPFTFGGNVLNTGLITNLPSKAVVEVTCVAD-----RKKITPCFAGELPEQLAALNRTNINTQLMTIEAAVTRKKEAVYQAAMLDPHTSAELSMKDIISMCDDLFAAHGDWLPEYK 3U95 Chain:A ((2-456)) --KISIVGAGSVRFALQLVEDIAQTDELSREDTHIYLMDVHERRLNASYILARKYVEELNSPVKVVKTESLDEAIEGADFIINTAYPYDPRYHDSGSQRWDEVT--KVGEKHGYYRGIDSQELNMVSTYTYVLSSYPDVKLALEIAEKMKKMAPKAYLMQTANPVFEITQAVRRWTGANIIGFCHGV-AGVYEVFERLGLDPEEVDWQVAGVNHGIWLNRFRYRGKDAYPLLDEWIEKELSKWEPKNPWDTQMSPAAMDMYRFYGMLPIGDTVRNGTWKYHYNLETKKKWFRR-FGGIDNEVERPKFHEHLRRARERL---IKLAEEVQENPHLKITEKHPEIFPKGRLSGEQHIPFINAIANNKRVRLFLNVENQGALKDFPDDLVMELPVWVDSSGIHREKVEPDLTHRI--KIFYLWPRILRTE-WNLEAFISRDRKVLEEILIRDPRTK---SYEQVVKVLDEILS----------

General information: TITO was launched using: RESULT: Template: 3U95.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2232 61188 27.41 150.34 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : 27.41 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.391

(partial model without unconserved sides chains): PDB file : Tito_3U95.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3U95-query.scw PDB file : Tito_Scwrl_3U95.pdb: