Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYFVDRSKIEKTLGFFEHQLALFDSQTDWQSEIGELA----LQRIGHLLIECILDTGNDMIDGFIM--RDPGSY--DDIMDILVDEKVVTEKEGDELKKLIAYRKTLVQQYLLADSGELYRLIKAHQTALQDFPKRIRSYLETELGPVSAFK 2G9B Chain:A ((151-249)) -------------------LKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQELDINNISTYKKNIMA---LSDGGKLYR-------------------------------

General information: TITO was launched using: RESULT: Template: 2G9B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 264 14199 53.78 156.03 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 53.78 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.163

(partial model without unconserved sides chains): PDB file : Tito_2G9B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2G9B-query.scw PDB file : Tito_Scwrl_2G9B.pdb: