Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNIAVVTDSTAYIPKEMREQHQIHMIPLQVVF---REETYREEIELDWKSFYEEVKKHNELPTTSQPPIGELVALYEELGK-SYDAVISIHLSSGISGTFSSAAAADSMVDNIDVYPFDSEISCLAQGFYALKAAELIKNGASSPEDIIKELEEMKKT--VRAYFMVDDLAHLQRGGRLSSAQAFIGSLLKVKPILHFDNKVIVPFEKIRTRKKAISRIYELLDEDASKGLPMRAAVIHANREEEAAKIIEELSAKYPHVEFYNSYFGAVIGTHLGEGALGICWCFK 1MGP Chain:A ((28-303)) --VKILVDSTADVPFSWMEKYDIDSIPLYVVWEDGRSEPDEREPE-EIMNFYKRIREAGSVPKTSQPSVEDFKKRYLKYKEEDYDVVLVLTLSSKLSGTYNSAVLASKEVD-IPVYVVDTLLASGAIPLPARVAREMLENGATI-EEVLKKLDERMKNKDFKAIFYVSNFDYLVKGGRV---------LLKIRVCLHIENGELIPYRKVRGDKKAIEALIEKLREDTPEGSKLRVIGVHADNEAGVVELLNTLRKSYEVVDEIISPMGKVITTHVGPGTVG------

General information: TITO was launched using: RESULT: Template: 1MGP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1415 9609 6.79 36.82 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : 6.79 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.519

(partial model without unconserved sides chains): PDB file : Tito_1MGP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1MGP-query.scw PDB file : Tito_Scwrl_1MGP.pdb: