Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MANEFRVCD----------DCQATNIKTLLPRLKEVD-------PDAKVEV-GCQSYCGPGRKKSFAFVN--NRPLSAPTEDELIDKVKKKIKK 1M2D Chain:A ((4-90)) --KHVFVCVQDRPPGHPQGSCAQRGSREVFQAFMEKIQTDPQLFMTTVITPTGCMNASMM---GPVVVVYPDGVWYGQVKPEDVDEIVEKHL--

General information: TITO was launched using: RESULT: Template: 1M2D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 239 -2960 -12.38 -44.18 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -12.38 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.628

(partial model without unconserved sides chains): PDB file : Tito_1M2D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1M2D-query.scw PDB file : Tito_Scwrl_1M2D.pdb: