Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDQQSTRTDITVNVDGFWMLQALLDIRHVAPELRCRPYVSTDSNDWLNEHPGMAVMREQGIVVNDAVNEQVAARMKVLAAPDLEVVALLSRGKLLYGVIDDENQPPGSRDIPDNEFRVVLARRGQHWVSAVRVGNDI---------TVDDVTVSDSASIAALVMDGLESIHHADPAAINAVNVPMEEMLEATKSWQESGFNVFSGGDLRRMGISAATVAALGQALSDPAAEVAVYARQYRDDAKGPSASVLSLKDGSGGRIALYQQARTAGSGEAWLAICPATPQLVQVGVKTVLDTLPYGEWKTHSRV 4W4I Chain:A ((73-293)) ----------------------------------------------------MGLLSPQGVI-----NPAVADWIKVVCFPDRW--------------LDLRYVGPASADGACELLRGIVALRTGTGK---KTGNGVVALRNAQLVTFTAMDIDDPRALVPILGVGLA---HRPPARFDEFSLPTRVGARADERLRS---GVPLGEVVDYLGIPASARPVVESVFSGPRSYVEIVAGCNRDGRHTTTEVGLSIVDTSAGRV-LVSPSR-AFDGEWVSTFSPGTPFAIAVAIQTLTACLPD---------

General information: TITO was launched using: RESULT: Template: 4W4I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -70979 for 1457 contacts (-48.7/contact) + 2D Compatibility (PS) -21445 + (NN) -1974 + (LL) 5920 1D Compatibility (HY) -10800 + (ID) 2850 Total energy: -102128.0 ( -70.09 by residue) QMean score : 0.400

(partial model without unconserved sides chains): PDB file : Tito_4W4I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4W4I-query.scw PDB file : Tito_Scwrl_4W4I.pdb: