Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYS-MLAACFEPDVACEITLQPIRRY-DVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDP-QAIQPVLVAASLLVAEL-GDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHALMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAAL-GEHG---VPMTHFGVGTAELLGAMSEAVTAGERPGRGA-VVGVDWRTPLTDAAARVVPGTALQGNLDPAVVLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL 4WSH Chain:A ((12-357)) ------LKNDRFLRALLKQPVDVTPVWMMRQAGRYLPEYRATRAKAGDFMSLCMNPELACEVTLQPLDRYPQLDAAILFSDILTIPDAMGQGLYFETGEGPRFRKVVSSLADIEALPVPDPEQDLGYVMDAVRTIRRELNGRVPLIGFSGSPWTLATYMVEGGSSKDFRKSKAMLYDNPKAMHALLDKLAQSVTSYLNGQIHAGAQAVQIFDSWGGSLSAAAYQEFSLAYMRKIVDGLIREHDGRRVPVILFTKGGGLWLESMAEV---------GAEALGLDWTCDIGSARARVGERVALQGNMDPSVLYAN-PAAIRAEVARI----LAAYGKGTGHVFNLGHGITPEVDPAHAGAFFEAVHEL

General information: TITO was launched using: RESULT: Template: 4WSH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -262198 for 3021 contacts (-86.8/contact) + 2D Compatibility (PS) -36554 + (NN) -15623 + (LL) 496 1D Compatibility (HY) -24800 + (ID) 7450 Total energy: -346129.0 ( -114.57 by residue) QMean score : 0.534

(partial model without unconserved sides chains): PDB file : Tito_4WSH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4WSH-query.scw PDB file : Tito_Scwrl_4WSH.pdb: