Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAEVLVLVEHAEGALKKVSAELITAARALGEPAAVVVGVPGTAAPLV--DGLKAAGAAKIYVAESDLVDKYLITPAVDVLAGLAESSAPAGVLIAATADGKEIAGRLAARIGSGLLVDVVDVREGGVGVHSIFGGAFTVEAQANGDTPVITVRAGAVEAEPAAGAGEQVSVEVPAAAENAARITAR--EPAVAGDRPELTEATIVVAGGRGVGSAENFSVVEALADSLGAAVGASRAAVDSGYYPGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADYGVVGDLFKVAPQLTEAIKARKG 2A1T Chain:R ((23-333)) ----LVIAEHANDSLAPITLNTITAATRLGGEVSCLVA--GTKCDKVAQDLCKVAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDA--AATSGGSASSE-KASSTSPVEISEWLDQKLT---RPELTGAKVVVSGGRGLKSGENFKLLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK--

General information: TITO was launched using: RESULT: Template: 2A1T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -205848 for 2525 contacts (-81.5/contact) + 2D Compatibility (PS) -32890 + (NN) -13358 + (LL) 644 1D Compatibility (HY) -25200 + (ID) 6650 Total energy: -283302.0 ( -112.20 by residue) QMean score : 0.517

(partial model without unconserved sides chains): PDB file : Tito_2A1T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2A1T-query.scw PDB file : Tito_Scwrl_2A1T.pdb: