Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVDGFVQPVGEGLADQLVGHQVGYGGVQWDQCLAEVGDVAVVHFFHQ--------AVRQVGFVEQGVEAVVAGEQRRRGEEELLGDLQHRLDPFLDAGFA-------------GHAVGGVEQVRYLFDVGVDEAGEYVFRVLALRLDGAMQVGQAAGYQISQVTVAGFAEVRLLDEFTEGSGVHGVSHTTGMVKKRRNIAGGARRLRRDCHNRFVVMRG 4DGQ Chain:A ((25-111)) -------------------------------------DAKVIHFHHGWPLSSDDWDAQLLFFVNKGFR-VVAHDRRGHGRSSQVWD-GHDMDHYADDAAAVVEKLGTHGAMHVGHSTGGGEVVRYIARHGERNVSKAVLISSVPPLMVKTSSNPNGTPKSVFDDFQAHVAANRAQFYLDVPAGPFYGYNRPGAKPSEGVIYNWWRQGMMGSTKAQYDGI

General information: TITO was launched using: RESULT: Template: 4DGQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -9288 for 388 contacts (-23.9/contact) + 2D Compatibility (PS) -6947 + (NN) 101 + (LL) 2232 1D Compatibility (HY) -2800 + (ID) 1300 Total energy: -18002.0 ( -46.40 by residue) QMean score : 0.132

(partial model without unconserved sides chains): PDB file : Tito_4DGQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DGQ-query.scw PDB file : Tito_Scwrl_4DGQ.pdb: