Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHQRIASIGLGLTLALGGSAQAAGQLNVVSWSGYFSPQLLEKFEKESGIRVTVDSYDSNETLLAKLKQGGAG-YDVAIPSQQFVPILVKEALLERFDPAAEPYYANLLDNLKKPAWDPEGAYSVPFIWGTTSVVLDG-ARYAGPADSYAVLYQPPEELRGRINMFDSVSEVVDMASLYLGIPLCSADPKQMQRVLELLKAQKPFVKTYSSKAGSIRENLAAGEVDMSMFWGGSSMRARELKPSLKYLYPKEGVLAWVDNLVIPRGSRNPDNARRFIAFLAQPENAALTQNFLKHQSPVKGVEPYLDASLKDAPELHVPAGTRVVFSQTCGEDAIRLADRLWTNLMR 1POT Chain:A ((6-273)) -------------------------LYFYNWTEYVPPGLLEQFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKSKLTNFSNLDPDMLNKPFDPNNDYSIPYIWGATAIGVNGDAVDPKSVTSWADLWKP--EYKGSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYNELKKLMPNVAAFNSDNPA--NPYMEGEVNLGMIWNGSAFVARQAGTPIDVVWPKEGGIFWMDSLAIPANAKNKEGALKLINFLLRPDVAKQVAETIGYPTPNLAARKLLSPEVANDKTLYPDAETIKNGEWQNDVGAASSIYEEYYQKLK

General information: TITO was launched using: RESULT: Template: 1POT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -112334 for 2180 contacts (-51.5/contact) + 2D Compatibility (PS) -28782 + (NN) -18891 + (LL) 1948 1D Compatibility (HY) -20800 + (ID) 4550 Total energy: -183409.0 ( -84.13 by residue) QMean score : 0.532

(partial model without unconserved sides chains): PDB file : Tito_1POT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1POT-query.scw PDB file : Tito_Scwrl_1POT.pdb: