Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKKSLLPLGLAIGLASLAASPLIQASTYTQTKYPIVLAHGMLGFDNILGVDYWFGIPSALRRDGAQVYVTEVSQLDTSEVRGEQLLQQVEEIVALSGQPKVNLIGHSHGGPTIRYVAAVRPDLIASATSVGAPHKGSDTADFLRQI-PPGSAGEAVLSGLVNSLGALISFLSSGSTGTQNSLGSLESLNSEGAARFNAKYPQGIPTSACGEGAYKVNGVSYYSWSG------SSPLTNFLDPSDAFLGASSLTFKNGTANDGLVGTCSSHLGMVIRDNYRMNHLDEVNQVFGLTSLFETSPVSVYRQHANRLKNASL 4GW3 Chain:A ((22-307)) ------------------------------STKYPIVLVHGLAGFNEIVGFPYFYGIADALRQDGHQVFTASLSAFNSNEVRGKQLWQFVQTLLQETQAKKVNFIGHSQGPLACRYVAANYPDSVASVTSINGVNHGSEIADLYRRIMRKDSIPEYIVEKVLNAFGTIISTFSGH--DPQDAIAALESLTTEQVTEFNNKYPQALPKTPGGEGDEIVNGVHYYCFGSYIQGLIAGEKGNLLDPTHAAMRVLN-TFFTEKQNDGLVGRSSMRLGKLIKDDYAQDHIDMVNQVAGLVG-YNEDIVAIYTQHAKYLASKQL

General information: TITO was launched using: RESULT: Template: 4GW3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -75390 for 2462 contacts (-30.6/contact) + 2D Compatibility (PS) -29971 + (NN) -9772 + (LL) 2716 1D Compatibility (HY) -24000 + (ID) 6000 Total energy: -142417.0 ( -57.85 by residue) QMean score : 0.509

(partial model without unconserved sides chains): PDB file : Tito_4GW3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4GW3-query.scw PDB file : Tito_Scwrl_4GW3.pdb: