Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEPFRNIGIIGRLGSTQVLDTIRRLKKFLIDRHLHVILEDTIAEVLPGHGLQTCSRKIMGEI-----CDLVVVVGGDGSMLGAARALARHKVPVLGINRGSLGFLTDIRPDELEAKVGEVLDGQYIVESRFLLDAQVRRGIDSMGQGDALNDVVLHPGKSTRMIEFELYIDGQFVCSQKADGLIVATPTGSTAYALSAGGPIMHPKLDAIVIVPMYPHMLSSRPIVVDGNSELKIVVSPNMQIYPQVSCDGQNHFTCAPGDTVTISKKPQKLRLIHPIDHNYYEICRTKLGWGSRLGGGD 1Y3H Chain:A ((5-274)) ----RSVLLVVHT-----TETARRVEKVLGDNK--IALRVLS--------------------HAADGCELVLVLGGDGTFLRAAELARNASIPVLGVNLGRIGFLAEAEAEAIDAVLEHVVAQDYRVEDRLTLDVVVRQGGRIVNRGWALNEVSLEKGPRLGVLGVVVEIDGRPVSAFGCDGVLVSTPTGSTAYAFSAGGPVLWPDLEAILVVPNNAHALFGRPMVTSPEATIAIEIEADGH-DALVFCDGRREMLIPAGSRLEVTR---------------------------------

General information: TITO was launched using: RESULT: Template: 1Y3H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -168462 for 1845 contacts (-91.3/contact) + 2D Compatibility (PS) -25748 + (NN) -12822 + (LL) 3324 1D Compatibility (HY) -17600 + (ID) 4200 Total energy: -225508.0 ( -122.23 by residue) QMean score : 0.451

(partial model without unconserved sides chains): PDB file : Tito_1Y3H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y3H-query.scw PDB file : Tito_Scwrl_1Y3H.pdb: