Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVFQHDIYAGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRHPRIRREELDI------TDSQRLQRLFEALPR--------LDVLVNNAGISR--DREEYDLATFERVLRLNLSAAMLASQ-LARPLLAQ-RGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGWIDTPLGAGLKADVEATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVLAVDGGYLCA 4HP8 Chain:A ((9-246)) ---------GRKALVTGANTGLGQAIAVGLAAAGAEVV--------CAARRAPD---ETLDIIAKDGGNASALLIDFADPLAAKDSFTDAGFDILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFFTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGINVNAIAPGYIETNNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFLSSAAADYVHGAILNVDGGWLA-

General information: TITO was launched using: RESULT: Template: 4HP8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -94420 for 1869 contacts (-50.5/contact) + 2D Compatibility (PS) -24193 + (NN) -13204 + (LL) 1752 1D Compatibility (HY) -18800 + (ID) 4950 Total energy: -153815.0 ( -82.30 by residue) QMean score : 0.529

(partial model without unconserved sides chains): PDB file : Tito_4HP8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HP8-query.scw PDB file : Tito_Scwrl_4HP8.pdb: