Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIYGIGLDITELKRIASMAGRQKRFAERILTRSELDQYYELS-EKRKNEFLAGRFAAKEAFSKAFGTGIGRQLSFQDIEIRKDQNGKPYIICTKLSQAAVHVSITHTKEYAAAQVVIERLSS 5CXD Chain:C ((4-119)) MIHGIGVDLIEIDRIQALYSKQPKLVERILTKNEQHKFNNFTHEQRKIEFLAGRFATKEAFSKALGTGLGKHVAFNDIDCYNDELGKPKI---DYEGFIVHVSISHTEHYAMSQVVLEK---

General information: TITO was launched using: RESULT: Template: 5CXD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 473 -61375 -129.76 -533.70 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain C : 0.86 3D Compatibility (PKB) : -129.76 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.446

(partial model without unconserved sides chains): PDB file : Tito_5CXD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CXD-query.scw PDB file : Tito_Scwrl_5CXD.pdb: