Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKITTNEQFN-ELIQSDKEIIVKFYADWCPDCTRMNMFIGDILEEYNQN-DWYELNKDELPDLAEKYQVMGIPSLLIFKNGEKTAHLHSANAKTPEEVTEFLSEHIS 2TRX Chain:A ((8-108)) -----TDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKG--QLKEFLDANLA

General information: TITO was launched using: RESULT: Template: 2TRX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 392 -60047 -153.18 -606.53 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -153.18 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.607

(partial model without unconserved sides chains): PDB file : Tito_2TRX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2TRX-query.scw PDB file : Tito_Scwrl_2TRX.pdb: