Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MAVNFYDVAYDLENALRGSEEFTRLKNLYDEVNADESAKRMFENFRDVQLRLQQKQMAGEEITQEEVTQAQKTVALVQQHEKISQLMEAEQRMSMLIGELNKIIMKPLEELYGSVEG 4OM3 Chain:A ((10-126)) KFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQQQLQAQHLSH-

General information: TITO was launched using: RESULT: Template: 4OM3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 56 -6121 -109.29 -52.76 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -109.29 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.390

(partial model without unconserved sides chains): PDB file : Tito_4OM3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OM3-query.scw PDB file : Tito_Scwrl_4OM3.pdb: