Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIVRIETFPLFHRLEKPYGDANGFKRYRTCYLIRIITESGIDGWGECVDW--LP-------ALHVGFTKRIIPFLLGKQAGSRLSLVRTI---QKWHQRAASAVSMALTEIAAKAADCSVCELWGGRYREEIPVYASFQSYSDSPQWISRSVSNVEA-QLKKGFEQIKVKIGGTSF-KEDVRHINALQHTAGSSITMILDANQSYDAAAAFKWERYFSEWTNIGWLEEPLPFDQPQDYAMLRSRLSVPVAGGENMKGPAQYVPLLSQRCLDIIQPDVMHVNGIDEFRDCLQLARYFGVRASAHAY-DGSLSRLYALFAQACLPPWSKM-KNDHIEPIEWDVMENPFTDLVSLQPSKGMVHIPKGKGIGTEINMEIVNRYKWDGSAY 2CHR Chain:A ((1-368)) MKIDAIEAVIVDVPTKRPIQMSITTVHQQSYVIVRVY-SEGLVGVGEGGSVGGPVWSAECAETIKIIVERYLAPHLLGTDAFNVSGALQTMARAVTGNASAKAAVEMALLDLKARALGVSIAELLGGPLRSAIPIAWTLA-SGDT--KRD--LDSAVEMIERRRHNRFKVKLGFR-SPQDDLIHMEALSNSLGSKAYLRVDVNQAWDEQVASVYIPELEA-LGVELIEQPVGRENTQALRRLSDNNRVAIMADESLSTLASAFDLARDRSVDVFSLKLCNMGGVSATQKIAAVAEASGIASYGGTMLDSTIGTSVALQLYSTVPS-LPFGCELI--GP-F-VLADTLS-HEPLEIRDYELQVPTGVGHGMTLDEDKVRQYAR-----

General information: TITO was launched using: RESULT: Template: 2CHR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2111 -216042 -102.34 -613.75 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -102.34 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.392

(partial model without unconserved sides chains): PDB file : Tito_2CHR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2CHR-query.scw PDB file : Tito_Scwrl_2CHR.pdb: