Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTRKPFIICDFDGTITMNDNII-NIMKTFAPPEWMALKDGVLSKTLSIKEGVGRMFGLLPSSLKEEITSFVLEDAKIREGFREFVAFINEHEIPFYVISGGMDFFVYPLLEGIVEKDRIYCNHASFDNDYIHIDWPHSCKGTCSNQCGCCKPSVIHELSEPNQYIIMIGDSVTDVEAAKLSDLCFARD-YLLNECREQNLNHLPYQDFYEIRKEIENVKEVQEWLQNKNAGESSLK 3M9L Chain:A ((2-198)) SLSEIKHWVFDMDGTLTIAVHDFAAIREALSIPAEDDILTHLA-A-LPADESAA--K---HAWLLEHERDLA-QGSRPAPGAVELVRELAGRGYRLGILTRNARELAHVTLEAIGL-ADCFAEADVL-GRDEAPPKPH----------PGGLLKLAEAWDVSPSRMVMVGDYRFDLDCGRAAGTRTVLVNLPDNPWP--ELTDWHARDCAQLRDLLSAE------------------

General information: TITO was launched using: RESULT: Template: 3M9L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 935 -124441 -133.09 -638.16 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -133.09 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.288

(partial model without unconserved sides chains): PDB file : Tito_3M9L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3M9L-query.scw PDB file : Tito_Scwrl_3M9L.pdb: